The wisdom and courage of the "Toyama medicine peddlers" who faced the turbulent Bakumatsu and Meiji Restoration periods. Miyamoto Literature's first historical epic novel, published in four consecutive months! Kawakami Yaichi, born in Etchu Toyama during the Bakumatsu period, throws himself into the industry of selling medicine, which the domain is promoting. Yaichi, who eventually becomes a traveling merchant in charge of the Satsuma domain, begins to notice a "secret agreement" connecting the medicine peddlers and the Satsuma domain. A grand story set against the backdrop of the arrival of the Black Ships and the crisis of the shogunate begins now.