After washing your face, apply it to your skin and just wait 30 seconds for it to dry! Gently pat areas where wrinkles are a concern. The feeling of firmness is amazing. Formulated with the cutting-edge complex ingredient "20s Exosome PDRN" to aim for skin that looks 20 years younger. You can, of course, apply makeup over it once it's dry. Serum Primer 6ml