Brand new, unopened. Medicated hand essence to prevent dry skin. Papilio's medicated hand serum prevents rough hands and maintains youthful hands full of firmness and elasticity. Active ingredients (glycyrrhetinic acid stearyl, DL-α-tocopherol acetate) prevent rough skin, such as chapped skin and cracks, and dryness, keeping skin smooth and supple. 8 types of Japanese and Chinese herbal extracts + 2 beauty ingredients. The yellow granules visible in the cream are a scrub-like concentration of 8 types of Japanese and Chinese herbal extracts (Scutellaria Baicalensis Root Extract, Paeonia Suffruticosa Root Extract, Phellodendron Amurense Bark Extract, Angelica Acutiloba Root Extract (1), Glycyrrhiza Extract, Coix Lacryma-Jobi Seed Extract, Lithospermum Erythrorhizon Root Extract, Panax Ginseng Root Extract) and two beauty ingredients, D-mannitol and crystalline cellulose. Thank you! This is a recent item.